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September 12
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A MyOvarianCancerTeam Member

Thanks Kaye for all your information and caring πŸ’•

7 days ago
A MyOvarianCancerTeam Member

Hi there Lisa, very good question about CA-125 and Elahere. 1390 to 881 after cycle 3 is a great response. I further looked into the range for additional data: Here goes:

It is highly encouraging that your CA-125 tumor marker numbers dropped significantly from 1390 to 881 after completing 3 cycles of Elahere, as this downward trend shows that your body is actively responding to the medication. While it is impossible to predict with absolute certainty whether the numbers will continue to fall, a steady decline is precisely what your oncology team looks for to confirm the treatment is working.

To better evaluate what might happen next, your doctor will look at a few critical clinical factors:
β€’ Overall Trend vs. Individual Fluctuations: Tumor markers can sometimes fluctuate or hit plateaus. Doctors look at the overall downward trajectory across multiple cycles rather than a single lab result.
β€’ Imaging and Scans: While tumor markers like CA-125 provide excellent clues, your doctor will correlate these numbers with CT, PET, or MRI scans to visually check if the tumors are shrinking or stabilizing.
β€’ The "350 to 290" Context: It looks like you might be comparing this to a previous drop (perhaps from an earlier line of treatment or a different point in your care). Every drug works differently;
is a targeted antibody-drug conjugate designed to continuously deliver therapy directly to folate receptor-alpha positive cancer cells, meaning its pattern of shrinking tumors can be entirely unique.
Ultimately, your oncology team is the only one who can definitively interpret these numbers based on your complete medical history.

I’m hoping your CA125 numbers will continue to fall but make sure as Elahere states, you maintain good eye protocol.
Hugs, KayeπŸ₯°

September 29
MyOvarianCancerTeam

That's genuinely encouraging news β€” seeing those CA-125 numbers drop from 1390 to 881 after cycle 3 of Elahere is a meaningful response worth celebrating! πŸŽ‰

It sounds like there may be two different sets of numbers being tracked here β€” possibly CA-125 and another marker. It's worth clarifying with your oncologist exactly Show Full Answer

That's genuinely encouraging news β€” seeing those CA-125 numbers drop from 1390 to 881 after cycle 3 of Elahere is a meaningful response worth celebrating! πŸŽ‰

It sounds like there may be two different sets of numbers being tracked here β€” possibly CA-125 and another marker. It's worth clarifying with your oncologist exactly what each number represents so you have a clear picture.

As for whether the numbers will continue to drop, here's what's generally known:

- Responses to treatment can vary from cycle to cycle
- A downward trend is a positive sign that the treatment is working
- Numbers don't always drop at the same rate β€” sometimes the decline slows, speeds up, or plateaus
- Each person's response is unique to their biology and cancer

The most important thing is that the overall trend is moving in the right direction. Your oncologist is the best person to interpret what these specific numbers mean for your treatment plan going forward, and whether any adjustments might be needed.

Keep tracking those numbers and don't hesitate to bring any questions or concerns to your care team β€” you know your body better than anyone!

September 12

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