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I am stage 4 low grade serous. Have had 3 rounds of carbo and Paxil to shrink my tumors. Got 50% shrinkage and am now scheduled for debulking surgery

March 17
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MyOvarianCancerTeam

Are you facing ongoing chemotherapy for stage 4 low-grade serous ovarian cancer?

It's understandable to feel overwhelmed by this news. For advanced ovarian cancer, ongoing or maintenance treatment is sometimes recommended to help control the disease long-term.

With low-grade serous carcinoma (LGSC), treatment approaches can Show Full Answer

Are you facing ongoing chemotherapy for stage 4 low-grade serous ovarian cancer?

It's understandable to feel overwhelmed by this news. For advanced ovarian cancer, ongoing or maintenance treatment is sometimes recommended to help control the disease long-term.

With low-grade serous carcinoma (LGSC), treatment approaches can vary. Your debulking surgery after achieving 50% shrinkage is a positive step - removing as much visible cancer as possible often leads to better outcomes.

After surgery, many people with advanced ovarian cancer receive additional chemotherapy or other treatments to help prevent recurrence. Some may need periodic treatment when cancer returns, while others might use maintenance therapies.

Treatment considerations for LGSC:
- Surgery to remove visible disease is often the primary treatment
- Chemotherapy may be used before or after surgery
- Hormone therapy is sometimes an option for stromal tumors
- Treatment plans are highly individualized based on how cancer responds

One study found that women with LGSC who had no visible cancer remaining after surgery had better outcomes. The goal is often managing the disease as a chronic condition rather than a one-time treatment.

It's worth having a detailed conversation with your oncologist about what "lifelong chemotherapy" means specifically for you - whether it's continuous, intermittent when needed, or maintenance therapy.

March 17

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