Dear Elisabeth, Have you been tested for KRAS Mutations? Helps in deciding which chemo to use.
Be sure to monitor with ca125 and He-4.
He-4 will be able to tell if chemo is working. It’s up to the oncologist how often to test. But was a good tool for my friend Cathy who had epithelial metastatic OC.
I’m hanging in there with you as well as our Teal sisters! A wonderful loving group!
🥰 Hugs Kaye

Hello Elisabeth,

I looked up using AI AND HERE ARE THE RESULTS.

For Stage 4 low-grade serous ovarian cancer (LGSOC) with metastasis to the sacrum, treatment focuses on a combination of surgical debulking, long-term hormonal management, and targeted therapies.

Because LGSOC is less responsive to traditional chemotherapy than high-grade types, clinical trials and specialized local treatments like radiation are often critical components of care.Standard Systemic TreatmentsHormonal Therapy:

This is a primary strategy for LGSOC as these tumors often have estrogen and progesterone receptors.

Common options include aromatase inhibitors like letrozole (Femara) or anastrozole (Arimidex), and medications like tamoxifen or fulvestrant.

Targeted Therapy:MEK Inhibitors:
Drugs such as trametinib (Mekinist) or the newly approved combination of avutometinib and defactinib (specifically for KRAS mutations) are used to block growth signals in LGSOC.Bevacizumab (Avastin):
An anti-angiogenesis drug often used alongside chemotherapy or on its own to cut off the blood supply to tumors.
Chemotherapy: Although response rates are lower for LGSOC, carboplatin and paclitaxel are still commonly used as a first-line starting treatment to slow disease progression

If I find out more data, will forward.
Sending big hugs 🥰 Kaye

My cancer is stage 4 low grade serous and inoperable. What are my options?