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Real members of MyOvarianCancerTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
January 20
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MyOvarianCancerTeam

Are others experiencing a slowly rising CA-125 while on exemestane for recurring low-grade serous carcinoma?

A slowly rising CA-125 over the past year could indicate that the cancer isn't responding as well to your current treatment. When CA-125 levels increase or plateau during treatment, it often suggests the treatment Show Full Answer

Are others experiencing a slowly rising CA-125 while on exemestane for recurring low-grade serous carcinoma?

A slowly rising CA-125 over the past year could indicate that the cancer isn't responding as well to your current treatment. When CA-125 levels increase or plateau during treatment, it often suggests the treatment approach may need to be adjusted.

Your healthcare team will likely want to evaluate whether exemestane is still the best option for you. They may recommend additional imaging tests or other assessments to get a complete picture of what's happening.

It's important to discuss these rising levels with your oncologist soon. They can help determine if:
- The increase is significant enough to warrant a treatment change
- Additional testing is needed
- A different therapy approach might be more effective

Low-grade serous carcinoma can be particularly challenging because it tends to grow more slowly and may not respond to treatments the same way high-grade cancers do. Your doctor will consider your overall health, symptoms, and other factors when deciding on next steps.

January 20

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