Can cold therapy mittens and booties help prevent peripheral neuropathy during Elahere (mirvetuximab soravtansine) treatment?
Cold therapy mittens and booties (also called cryotherapy gloves and socks) are sometimes used during chemotherapy infusions to help reduce nerve damage to the hands and feet. The idea is that cooling Show Full Answer
Can cold therapy mittens and booties help prevent peripheral neuropathy during Elahere (mirvetuximab soravtansine) treatment?
Cold therapy mittens and booties (also called cryotherapy gloves and socks) are sometimes used during chemotherapy infusions to help reduce nerve damage to the hands and feet. The idea is that cooling the extremities reduces blood flow to those areas, limiting how much of the drug reaches the nerves there.
However, it's important to know that Elahere's most commonly noted side effects lean more toward eye-related issues, such as:
- Blurry vision
- Eye irritation
- Dry eyes
Along with fatigue, nausea, and stomach discomfort. Peripheral neuropathy is more commonly associated with taxane-based chemotherapy drugs like paclitaxel. Whether cold therapy mittens and booties are effective or recommended specifically during Elahere infusions isn't well established yet, given how new this treatment is.
The best step is to ask the oncology care team directly before trying cold therapy during Elahere infusions, as they can advise based on the latest clinical guidance.
If neuropathy does occur, some approaches that have helped others include:
- Acupuncture or massage
- CBD creams or topical treatments
- Prescription medications like gabapentin or duloxetine
- Heat therapy for aching areas
June 26