Thank you for your information. I went to Moffett Cancer Center in FL...interesting that they have opposing views. I did have Avastin as part of my Frontline treatment...but Onc would not recommend for maintenance... I don't know what to do!! I wish you the best, as well!

Hi Debbie,

I was diagnosed with HGSC stage 3C last fall. I went for a second opinion at Sloan Kettering in NJ. I was so glad that I did. He talked me through my options, watch and wait(not for me), Avastin, or PARP. We decided on Avastin since I had ascites .
I started the Avastin with my last two rounds of chemotherapy. I have continued since 3/3/25. It has been a long year, I have struggled with joint and muscle pain daily, fatigue and neuropathy. I’m closing in on my last couple of months of Avastin infusions. My CA125 remains low. I know that the cancer is likely to return, but I have peace of mind knowing that I gave it my best shot. I also found out,from a local metastatic cancer group that going gluten and dairy free can help with the inflammation and therefore can lead to a decrease in pain. This has helped me tremendously! Wishing you all the best❣️

I went to a reknowned cancer center in Florida yesterday for a second opinion. The Oncologist told me she never prescribes Avastin alone as a maintenance drug due to dangerous side affects. Also Parpi inhibitors can cause destruction of bone marrow..so these drugs must only be prescribed if the benefits outweigh the risks...so I am now very comfortable not taking maintenance therapy at this time...I was a wreck when I finished my Frontline Therapy.

Did you experience major side effects?