Yes Beth, I have done the exact protocol you’re having. 2 rounds of Carbo, Taxol & Avastin then two rounds without Avastin, then debulking/cytroreduction with HIPEC. 7 days in hospital. I feel the HiPEC was probably the easiest part, no reaction from it. It was a 12 1/2 hour surgery, 2 blood transfusions, a colon resection lower end. After I had another 3 rounds of carbo & Taxol Declared NED, then started Zejula (BRCA 2+). During the next 6 months I really was on Zejula for only 3 1/2 months due to bad bloodwork and waiting for approval. At my 6 month check up, cancer had come back to my lymph nodes in pelvic and abdomen. Just had my 5th round of Carbo, Doxil & Avastin. Last CT Scan showed slowing of growth and no new areas. I am stage IIIc, HGSC, BRCA2+, HER2+, diagnosed 10/22. It is a very aggressive procedure, but believe it is well worth it to do it. I wish you the best and please keep us updated. 🩵🩵🙏🩵🩵

I know someone who had it done. She said she had no problems when she had it done. If it were me I would do it!!

Sorry Sharon I just saw this, my doctor felt the Zejula was a better choice. I believe all three parps are supposed to be best for BRACA, but didn’t turnout to be for me. He also stated that I most likely would not be put back on a PARP since the first one didn’t work. Avastin he said would probably be his choice until I start rejecting it. So we will see what happens in September once I get my next scan.

Hi Billie, I was wondering usually when people are Brca positive they are put on Lynparza. Why weren't you put on Lynparza right after chemo?