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Real members of MyOvarianCancerTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyOvarianCancerTeam Member asked a question ๐Ÿ’ญ
Berkeley, CA

Ive had ovarian cancer HGSerous since June 2021. I had a recurrence one my lung (a small nodule) in Feb 24, followed by doxolrubicon and then niraparib since Sept 2024. NED and low CA125. I'm afraid about going off niraparib...

June 8
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MyOvarianCancerTeam

It's completely understandable to feel anxious about the idea of stopping niraparib, especially when it's clearly working so well for you โ€” NED and a low CA125 is wonderful news! ๐ŸŽ‰

One MyOvarianCancerTeam member shared a similar experience, completing two years of Lynparza (olaparib, another PARP inhibitor) and described Show Full Answer

It's completely understandable to feel anxious about the idea of stopping niraparib, especially when it's clearly working so well for you โ€” NED and a low CA125 is wonderful news! ๐ŸŽ‰

One MyOvarianCancerTeam member shared a similar experience, completing two years of Lynparza (olaparib, another PARP inhibitor) and described feeling "a little scary to think that soon I'll be out here without that safety net." So those feelings are very real and very common. Regarding how long niraparib is typically taken, clinical trials like the PRIMA trial used it for up to three years or until cancer progressed. So continuing beyond two years is something that has been studied and may be an option worth discussing with your oncologist.

Key points to raise with your doctor:

- Whether continuing past two years is appropriate given your specific situation
- Regular monitoring, including blood tests and imaging, to track your response
- How to manage any side effects if continuing longer-term Every person's situation is unique, and your oncologist is best placed to weigh the benefits of continuing niraparib against any risks for your specific case. Being open about your fears with them is really important โ€” they can help guide that decision with you, not just for you.

June 8

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Sarasota, FL