My CA125 has not always been correct for me - so my doctor looks at it but only does treatment based on PET & CT Scans

There are many things that can cause your CA125 to increase. In my case it is my Auto-Immune disorder and the inflammation it causes which also causes my CA to increase.

I expect my Ca-125 will go up on the Thursday test. The hand-foot syndrome, associated with Doxorubicin, has advanced to blisters, inflammation and swelling of my feet and my arthritis has been barking like a dog. Depending on what percentage of rise is seen, a CT scan may be done after this, my 10th round, of Doxorubicin/Avastin or we’ll schedule it for after the 11th round. May even have to shoot a PET scan. I’ve had so many scans I’m amazed I don’t glow in the dark!

I had my 3 month check and my CA125 is still elevated but a bit lower than last check. My doctor is confused since my pet scan was negative so we wants me to have another one just to double check. It elevated during treatment up to 197 it came down and now it is at 152. We thought at that time it was because I had covid so she is interested in finding out if having had covid is keeping it elevated. I do also have arthritis so maybe that has something to do with it. She is not sure about that though.

There are factors that can cause increases in Ca-135. My gyn/onc explained the need to evaluate the percentage of increase in addition to findings on scans. Doubling is significant. Glad you picked up on it and got chemo going again. As we know the problem with OC is it’s adaptability with a propensity to reoccur.
Pray your next scan shows a good response 🙏💕